Full credit to Suauve9 - my hat tips to his research.
United States Patent 7,803,754
Chu , et al. September 28, 2010
Combination therapy for the treatment of diabetes and conditions
related thereto and for the treatment of conditions ameliorated by
increasing a blood GLP-1 level
Abstract
The present invention concerns combination of an amount of a GPR119
agonist with an amount of a dipeptidyl peptidase IV (DPP-IV) inhibitor
such that the combination provides an effect in lowering a blood
glucose level or in increasing a blood GLP-1 level in a subject over
that provided by the amount of the GPR119 agonist or the amount of the
DPP-IV inhibitor alone and the use of such a combination for treating
or preventing diabetes and conditions related thereto or conditions
ameliorated by increasing a blood GLP-1 level. The present invention
also relates to the use of a G protein-coupled receptor to screen for
GLP-1 secretagogues.
Inventors: Chu; Zhi-Liang (San Diego, CA), Leonard; James N. (San
Diego, CA), Al-Shamma; Hussien A. (Encinitas, CA), Jones; Robert M.
(San Diego, CA)
Assignee: Arena Pharmaceuticals, Inc. (San Diego, CA)
Appl. No.: 11/603,417
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7,803,754.PN.&OS=PN/7,803,754&RS=PN/7,803,754
No comments:
Post a Comment