Wednesday, September 29, 2010

New PATENT Awarded to ARNA - Combination therapy for the treatment of diabetes and conditions related thereto

Full credit to Suauve9 - my hat tips to his research.

United States Patent    7,803,754
Chu ,   et al.  September 28, 2010
Combination therapy for the treatment of diabetes and conditions
related thereto and for the treatment of conditions ameliorated by
increasing a blood GLP-1 level

Abstract

The present invention concerns combination of an amount of a GPR119
agonist with an amount of a dipeptidyl peptidase IV (DPP-IV) inhibitor
such that the combination provides an effect in lowering a blood
glucose level or in increasing a blood GLP-1 level in a subject over
that provided by the amount of the GPR119 agonist or the amount of the
DPP-IV inhibitor alone and the use of such a combination for treating
or preventing diabetes and conditions related thereto or conditions
ameliorated by increasing a blood GLP-1 level. The present invention
also relates to the use of a G protein-coupled receptor to screen for
GLP-1 secretagogues.
Inventors:      Chu; Zhi-Liang (San Diego, CA), Leonard; James N. (San
Diego, CA), Al-Shamma; Hussien A. (Encinitas, CA), Jones; Robert M.
(San Diego, CA)
Assignee:       Arena Pharmaceuticals, Inc. (San Diego, CA)
Appl. No.:      11/603,417

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7,803,754.PN.&OS=PN/7,803,754&RS=PN/7,803,754

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